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Nilotinib is at present accepted by FDA as entrance-line therapy for Long-term stage CML and for patients that are resistant or intolerant to imatinib.The magnificent effects demonstrated with imatinib mesylate (aka Gleevec) focusing on split point cluster (Bcr)-Abelson (Abl) fusion protein in Long-term myeloid leukemia (CML) result in the developm